Epigenetics research programs

Students also present their findings in research-in-progress meetings, which are attended by their peers and the faculty. Student invited speakers, small group teaching experiences, and training in the ethical conduct of research round out the overall list of activities that occur as students conduct research and prepare their dissertation. Research interests of the faculty vary in topic, approach and model organism.

More on Research Opportunities The graduate program in Genetics and Molecular Biology GMB at Emory University offers an exciting broad based training in the fields of genetics and molecular biology and their related disciplines of biochemistry, bioinformatics, cell biology, developmental biology and statistics.

A wide range of research opportunities in bacterial, viral, human and eukaryotic model system genetics enable students to specialize in their area of interest while obtaining an essential foundation in genetics. Clinical Chemistry and Toxicology. Medical Automation Research. Neurotransmitters, cell surface receptors and intracellular second messengers.

Acute Myeloid Leukemia: molecular and cellular biology events which mediate aberrant epigenetic and transcriptional mechanisms during disease establishment and progression. Regulation of stem cell function and tumorigenesis by epigenetics and biomolecular condensation phase separation. Genetic variation, Complex diseases, Coronary artery disease, Genomics, Epigenomics, Regulatory mechanisms, Vascular biology, Pharmacology and Physiology.

Cell signaling, hematopoietic stem cell biology, molecular and epigenetic mechanisms of leukemia. Genetic basis of common human disease, including type 1 diabetes, diabetic complications, ischemic stroke, atherosclerosis.

Investigation of the neuronal circuits and epigenetic modifications involved in the control of food intake, impulsivity and novelty seeking behavior.

Mechanisms of chromosome segregation in Mitosis and generation of Chromosomal Instability in tumors. The research team has been tracking abnormalities in blood, as well as epigenetic changes, which may serve as indicators, or markers, of exposure to air pollution and toxic metals at levels that can increase the risk of cardiovascular disease, particularly in elderly men.

These markers may help in the early detection and prevention of cardiovascular and other diseases. Grantees at Beth Israel Deaconess Medical Center used epigenetics to define the link between environmental exposure to smoke, mercury, and lead, and reproductive outcomes, such as preterm birth. NIEHS scientists in the Epigenetics and Stem Cell Biology Laboratory are examining how epigenetic mechanisms influence normal cell development, and contribute to biological processes involved in breast cancer and immune function.

The research is helping to identify what genes are regulated by the complex and how the complex alters epigenetic processes that may contribute to disease. Understanding the underlying mechanisms of disease may lead to the development of new methods to diagnose, prevent, and treat diseases, such as breast cancer, in the future.

NIEHS-supported researchers have found that early-life exposure to nutritional and dietary factors, maternal stress, and environmental chemicals can increase the likelihood of developing disease and poor health outcomes later in life. In addition, some of the effects of these exposures can be passed down for multiple generations, even after the original exposure has been removed, through a process known as transgenerational inheritance.

Researchers in the NIEHS Transgenerational Inheritance in Mammals After Environmental Exposure TIME Program are using mice and rats to investigate how transgenerational inheritance occurs after exposure to environmental exposures, whether the process is different in males and females, and when in development these events are most likely to occur. Understanding how transgenerational inheritance of effects from exposures occur in animals may shed light on similar processes in humans.

Use the browser controls to adjust the font size, or print this page. Further Reading. Epigenetic differences arise during the lifetime of monozygotic twins. PNAS 30 Transposable elements: targets for early nutritional effects on epigenetic gene regulation.

Mol Cell Biol 23 15 Integrative analysis of reference human epigenomes. Nature Air pollution and markers of coagulation, inflammation, and endothelial function: associations and epigene-environment interactions in an elderly cohort.